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AZT-<sup>13</sup>C,d<sub>3</sub>

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-17413S1

    Azidothymidine-<sup>13sup>C,d<sub>3sub>; AZT-<sup>13sup>C,d<sub>3sub>; ZDV-<sup>13sup>C,d<sub>3sub>

    Isotope-Labeled Compounds HIV CRISPR/Cas9 Infection
    Zidovudine- 13C,d3 is the 13C- and deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. Zidovudine-13C,d3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
    Zidovudine-13C,d3

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